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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP9
All Species:
10.3
Human Site:
S307
Identified Species:
18.89
UniProt:
P55211
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55211
NP_001220.2
416
46281
S307
S
T
S
P
E
D
E
S
P
G
S
N
P
E
P
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
I172
G
T
E
L
D
C
G
I
E
T
D
S
G
V
D
Rhesus Macaque
Macaca mulatta
XP_001082859
416
46192
S307
S
T
S
P
E
D
E
S
S
G
S
N
P
E
P
Dog
Lupus familis
XP_865164
414
45235
S306
S
A
S
P
E
D
R
S
P
G
S
D
S
E
P
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
D330
D
E
T
D
R
G
V
D
Q
Q
D
G
K
N
H
Rat
Rattus norvegicus
P55215
452
50709
D330
D
E
T
D
R
G
V
D
Q
Q
D
G
K
N
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520982
366
40213
P257
L
D
S
P
E
D
H
P
T
G
S
D
P
E
S
Chicken
Gallus gallus
Q98943
424
47941
D301
D
E
T
D
R
G
V
D
Q
R
D
G
K
E
R
Frog
Xenopus laevis
P55866
282
32106
T177
F
I
Q
A
C
R
G
T
E
L
D
S
G
I
E
Zebra Danio
Brachydanio rerio
NP_001007405
436
48445
D322
Q
P
S
I
G
G
I
D
D
E
M
D
A
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
S218
V
T
E
T
D
G
E
S
S
T
S
Y
K
I
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
R381
D
G
V
P
A
F
L
R
R
G
W
D
N
R
D
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
Q321
A
K
P
Q
V
D
A
Q
I
N
D
E
E
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
93.9
76.9
N.A.
28.9
28.3
N.A.
52.8
31.1
22.6
47.2
N.A.
22.1
N.A.
21.6
32.2
Protein Similarity:
100
35.8
96.8
84.1
N.A.
46.9
46.2
N.A.
65.6
48.3
38.7
64.2
N.A.
35.8
N.A.
37.5
51
P-Site Identity:
100
6.6
93.3
73.3
N.A.
0
0
N.A.
53.3
6.6
0
13.3
N.A.
33.3
N.A.
13.3
6.6
P-Site Similarity:
100
20
93.3
80
N.A.
6.6
6.6
N.A.
60
13.3
13.3
20
N.A.
40
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
8
0
8
0
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
8
0
24
16
39
0
31
8
0
47
31
0
0
16
% D
% Glu:
0
24
16
0
31
0
24
0
16
8
0
8
8
39
8
% E
% Phe:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
8
39
16
0
0
39
0
24
16
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
16
% H
% Ile:
0
8
0
8
0
0
8
8
8
0
0
0
0
24
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
31
0
0
% K
% Leu:
8
0
0
8
0
0
8
0
0
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
16
8
16
0
% N
% Pro:
0
8
8
39
0
0
0
8
16
0
0
0
24
0
39
% P
% Gln:
8
0
8
8
0
0
0
8
24
16
0
0
0
0
0
% Q
% Arg:
0
0
0
0
24
8
8
8
8
8
0
0
0
8
8
% R
% Ser:
24
0
39
0
0
0
0
31
16
0
39
16
8
0
8
% S
% Thr:
0
31
24
8
0
0
0
8
8
16
0
0
0
0
0
% T
% Val:
8
0
8
0
8
0
24
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _